Fig. 1

The high expression of SFN promotes the cellular process of CC cells. a. RT-qPCR was used to detect SFN expression in normal tissues and CC tissues, as well as normal cell (Ect1-E6E7) and CC cells (HeLa, SiHa, CaSki, C33a). b. The expression of SFN was assessed by RT-qPCR and western blot assays after transfecting with sh-SFN#1 and sh-SFN#2 in HeLa and SiHa cell lines. c-e. Colony formation assay, EdU stained assay and CCK-8 assay were performed to estimate cell proliferation. f. Western blot analysis of apoptosis related protein (Bax and Bcl-2) levels. g. Flow cytometry analysis was used to determine cell apoptotic ability. *p < 0.05, **p < 0.01