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Table 2 Sensitivity, specificity, PPV, NPV, and accuracy of serum FGF19 levels and the existing markers alone and in combination in all the HCC cases

From: Serum fibroblast growth factor 19 serves as a potential novel biomarker for hepatocellular carcinoma

 Sensitivity (%)Specificity (%)PPV (%)NPV (%)Accuracy (%)
Single marker
 AFP44.496.596.444.861.0
 DCP62.295.596.952.970.9
 FGF1953.295.195.948.766.6
Double markers
 AFP and DCP73.791.795.361.077.6
 AFP and FGF1976.091.595.164.080.9
 DCP and FGF1981.391.095.468.882.5
Multiple markers
 AFP, DCP, and FGF1987.587.294.076.385.7