Fig. 3
From: EZH2 upregulation by ERα induces proliferation and migration of papillary thyroid carcinoma

Estrogen upregulated EZH2 to promote the PTC cell proliferation and migration.a The proportional morbidity rates of PTC in female and male patients with PTC. b K1 and W3 cell lines were treated with 10 nM E2 for 24 h, and then were analyzed by western blotting. c and d K1 and W3 cell lines were treated with 10 nM E2 and 2 μM GSK126, and then were analyzed by CCK8, Colony formation assays and transwell migration assay. Data represent the mean ± S.E.M. *P < 0.05