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Table 1 ROS-related genes were used to construct the score

From: A reactive oxygen species scoring system predicts cisplatin sensitivity and prognosis in ovarian cancer patients

Gene Symbol

P

Survival

Name

AKT2

0

low

V-akt murine thymoma viral oncogene homolog 2

FOSB

0.005

low

FBJ murine osteosarcoma viral oncogene homolog B

CITED4

0.009

high

Cbp/p300-interacting transactivator

CYBA

0.012

high

Cytochrome b-245, alpha polypeptide

JUNB

0.013

low

Jun B proto-oncogene

CYP27B1

0.014

high

Cytochrome P450, family 27, subfamily B, polypeptide 1

FOS

0.014

low

FBJ murine osteosarcoma viral oncogene homolog

NFIX

0.027

low

Nuclear factor I/X

TXNRD1

0.041

low

Thioredoxin reductase 1

USP14

0.054

high

Ubiquitin specific peptidase 14

RIT1

0.058

low

Ras-like without CAAX 1

KEAP1

0.0581

high

Kelch-like ECH-associated protein 1

CYP3A7

0.061

high

Cytochrome P450, family 3, subfamily A, polypeptide 7

TXN

0.07

low

Thioredoxin

GCLC

0.07

high

Glutamate-cysteine ligase, catalytic subunit

AKR7A3

0.072

low

Aldo-keto reductase family 7, member A3

JUN

0.074

low

Jun proto-oncogene

CUL3

0.076

low

Cullin 3

GSTA3

0.076

high

Glutathione S-transferase alpha 3

PMF1

0.078

high

Polyamine-modulated factor 1

PPARG

0.106

low

Peroxisome proliferator-activated receptor gamma

SOD1

0.122

high

Superoxide dismutase 1, soluble

ABCC4

0.123

high

ATP-binding cassette, sub-family C, member 4

GSTM3

0.14

low

Glutathione S-transferase mu 3 (brain)

NOX4

0.142

high

NADPH oxidase 4

  1. NOTE: “High” indicates that gene expression above the median gene expression was associated with better overall survival; “low” indicates that gene expression above the median gene expression was associated with poor overall survival