MicroRNAs in Pancreatic Cancer: biomarkers, prognostic, and therapeutic modulators

BMC Cancer

Table 1 miRNAs as biomarkers in pancreatic cancer (“= high mainly in early lesions)

miRNA	Analysis Technique	Normal Pancreatic Tissues	Pancreatitis	PC	Cell lines	Reference
-20a, −29c 96, − 141,	Microarray	High	N/A	Low	N/A	[78]
-10a, −10b, − 204, − 372,	Microarray	Low	N/A	High	N/A	[82]
-93, −133a, − 203, − 205, − 210, − 224	Microarray	Low	N/A	High	High	[60]
-27a	Microarray	Low	N/A	High	N/A	[78]
-221, −222	Microarray, qRT-PCR	Low	N/A	High	High	[60, 79]
-216, −217	Microarray	Very high	N/A	Very low	Very low	[60, 78]
-200a	Microarray, TaqMan low density array, qRT-PCR	Low	N/A	High	N/A	[78, 81]
-200a	Microarray	High	N/A	Low	N/A	[60]
-196a	Microarray, qRT-PCR	Absent	Absent	High	High	[60, 78, 79]
-15b, −95, −186, −190, −200b	qRT-PCR	Low	N/A	High	N/A	[79]
-146a	Microarray	Low	N/A	High	N/A	[78, 82]
−143, −145, −150	Microarray	Low	High	High	Absent	[60]
−141, −148a, −200b, −200c, −375	Microarray, TaqMan low density array, qRT-PCR	Low	N/A	N/A	High	[80]
−139, −142, −345	qRT-PCR	Low	N/A	Low	N/a	[76]
−100, −125b-1, −212, −301, −424	qRT-PCR	Low	N/A	High	N/a	[76]
−21	Microarray, TaqMan low density array, qRT-PCR	Low	N/A	High “	High	[77, 78, 80, 81]
−155	qRT-PCR	Low	N/A	High “	N/A	[77]
−205	qRT-PCR	Low	N/A	High “	N/A	[81]
−375	Microarray	High	Low	Low	Absent	[60]

ISSN: 1471-2407