Table 2 Multivariable Cox regression of systemic recurrence-free survival and breast cancer–specific survival in operable breast cancer patients (n = 191) according to pre-operative DTC status after median 15.3 years of follow-up

Systemic recurrence-free survival

Pre-operative DTC status (pos. vs neg.)

2.94

1.385–6.339

0.006

Post-operative DTC status (pos. vs neg.)

2.87

1.335–6.184

0.007

MAI status (high vs low)

2.65

1.352–5.186

0.005

Breast cancer–specific survival

Pre-operative DTC status (pos. vs neg.)

3.48

0.008

Post-operative DTC status (pos. vs neg.)

2.67

0.043

MAI status (high vs low.)

4.35

< 0.001