Table 4 Differences between responder and non-responder groups for DCE-MRI parameters with VS-GR/GRASP reconstruction
parameters | VS-GR reconstruction | GRASP reconstruction | ||||||
|---|---|---|---|---|---|---|---|---|
responder | non-responder | U value | P value | responder | non-responder | U value | P value | |
Ktrans max | 0.314 (0.000,1.097) | 2.303 (1.172,3.564) | 51.0 | <0.001 | 0.101 (0.000,0.189) | 0.304 (0.196,0.415) | 69.0 | 0.002 |
Ktrans mean | 0.055 (0.000,0.298) | 0.299 (0.157,0.387) | 92.0 | 0.007 | 0.031 (0.000,0.067) | 0.065 (0.046,0.094) | 104.0 | 0.015 |
Ktrans 75% | 0.069 (0.000,0.395) | 0.404 (0.200,0.545) | 92.0 | 0.007 | 0.043 (0.000,0.097) | 0.082 (0.061,0.121) | 115.0 | 0.027 |
Kep max | 1.088 (0.000,3.309) | 4.272 (2.307,6.527) | 90.0 | 0.007 | 0.559 (0.000,0.934) | 1.342 (0.861,1.875) | 75.0 | 0.002 |
Kep mean | 0.149 (0.000,0.751) | 0.506 (0.251,0.823) | 140.0 | 0.088 | 0.160 (0.000,0.340) | 0.318 (0.212,0.432) | 117.0 | 0.030 |
Kep 75% | 0.384 (0.000,1.095) | 0.772 (0.363,1.334) | 154.0 | 0.155 | 0.215 (0.000,0.509) | 0.429 (0.268,0.536) | 137.0 | 0.077 |
Ve max | 1.000 (1.000,1.000) | 1.000 (1.000,1.000) | 199.5 | 0.099 | 1.000 (0.736,1.000) | 1.000 (0.875,1.000) | 223.0 | 0.979 |
Ve mean | 0.030 (0.000,0.388) | 0.323 (0.201,0.370) | 124.0 | 0.042 | 0.163 (0.000,0.207) | 0.227 (0.189,0.276) | 93.0 | 0.008 |
Ve 75% | 0.006 (0.000,0.471) | 0.475 (0.297,0.521) | 112.0 | 0.023 | 0.187 (0.000,0.250) | 0.250 (0.209,0.311) | 104.0 | 0.015 |
Vp max | 0.017 (0.000,0.068) | 0.140 (0.056,0.316) | 71.0 | 0.002 | 0.046 (0.000,0.070) | 0.133 (0.085, 0.233) | 63.0 | 0.001 |
Vp mean | 0.0004 (0.0000,0.0048) | 0.002 (0.001,0.006) | 135.0 | 0.071 | 0.001 (0.000,0.009) | 0.014 (0.008,0.030) | 67.0 | 0.001 |
Vp 75% | 0.001 (0.001,0.001) | 0.001 (0.001,0.001) | 142.0 | 0.096 | 0.001 (0.000,0.012) | 0.023 (0.008,0.042) | 65.0 | 0.001 |
AUC max | 0.050 (0.000,0.076) | 0.108 (0.085,0.137) | 40.0 | <0.001 | 1.062 (0.000,2.220) | 3.424 (2.489,4.832) | 31.0 | <0.001 |
AUC mean | 0.016 (0.000,0.040) | 0.039 (0.030,0.047) | 90.0 | 0.007 | 0.569 (0.000,1.236) | 1.515 (1.188,1.901) | 60.0 | 0.001 |
AUC 75% | 0.020 (0.000,0.049) | 0.052 (0.052,0.060) | 86.0 | 0.005 | 0.753 (0.000,1.497) | 1.854 (1.403,2.203) | 55.0 | 0.001 |