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Table 4 Differences between responder and non-responder groups for DCE-MRI parameters with VS-GR/GRASP reconstruction

From: The value of GRASP on DCE-MRI for assessing response to neoadjuvant chemotherapy in patients with esophageal cancer

parameters VS-GR reconstruction GRASP reconstruction
responder non-responder U value P value responder non-responder U value P value
Ktrans max 0.314 (0.000,1.097) 2.303 (1.172,3.564) 51.0 <0.001 0.101 (0.000,0.189) 0.304 (0.196,0.415) 69.0 0.002
Ktrans mean 0.055 (0.000,0.298) 0.299 (0.157,0.387) 92.0 0.007 0.031 (0.000,0.067) 0.065 (0.046,0.094) 104.0 0.015
Ktrans 75% 0.069 (0.000,0.395) 0.404 (0.200,0.545) 92.0 0.007 0.043 (0.000,0.097) 0.082 (0.061,0.121) 115.0 0.027
Kep max 1.088 (0.000,3.309) 4.272 (2.307,6.527) 90.0 0.007 0.559 (0.000,0.934) 1.342 (0.861,1.875) 75.0 0.002
Kep mean 0.149 (0.000,0.751) 0.506 (0.251,0.823) 140.0 0.088 0.160 (0.000,0.340) 0.318 (0.212,0.432) 117.0 0.030
Kep 75% 0.384 (0.000,1.095) 0.772 (0.363,1.334) 154.0 0.155 0.215 (0.000,0.509) 0.429 (0.268,0.536) 137.0 0.077
Ve max 1.000 (1.000,1.000) 1.000 (1.000,1.000) 199.5 0.099 1.000 (0.736,1.000) 1.000 (0.875,1.000) 223.0 0.979
Ve mean 0.030 (0.000,0.388) 0.323 (0.201,0.370) 124.0 0.042 0.163 (0.000,0.207) 0.227 (0.189,0.276) 93.0 0.008
Ve 75% 0.006 (0.000,0.471) 0.475 (0.297,0.521) 112.0 0.023 0.187 (0.000,0.250) 0.250 (0.209,0.311) 104.0 0.015
Vp max 0.017 (0.000,0.068) 0.140 (0.056,0.316) 71.0 0.002 0.046 (0.000,0.070) 0.133 (0.085, 0.233) 63.0 0.001
Vp mean 0.0004 (0.0000,0.0048) 0.002 (0.001,0.006) 135.0 0.071 0.001 (0.000,0.009) 0.014 (0.008,0.030) 67.0 0.001
Vp 75% 0.001 (0.001,0.001) 0.001 (0.001,0.001) 142.0 0.096 0.001 (0.000,0.012) 0.023 (0.008,0.042) 65.0 0.001
AUC max 0.050 (0.000,0.076) 0.108 (0.085,0.137) 40.0 <0.001 1.062 (0.000,2.220) 3.424 (2.489,4.832) 31.0 <0.001
AUC mean 0.016 (0.000,0.040) 0.039 (0.030,0.047) 90.0 0.007 0.569 (0.000,1.236) 1.515 (1.188,1.901) 60.0 0.001
AUC 75% 0.020 (0.000,0.049) 0.052 (0.052,0.060) 86.0 0.005 0.753 (0.000,1.497) 1.854 (1.403,2.203) 55.0 0.001
  1. Note. —Data are median (P25, P75)