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Table 1 Characteristics of Studies Included

From: Laparoscopic versus open major liver resection for hepatocellular carcinoma: systematic review and meta-analysis of comparative cohort studies

Reference/Country/Journal (year) Study Period (year) Study type Sample Size (n, y) Sex ratio (M/F) Cirrhosis (y/n), or ICGR15
LMLR OMLR LMLR OMLR LMLR OMLR
Cho JY/Korea/ Surgery(2015) [23] 2003–2012 R 24 (53.9 ± 12.6) 19 (60.0 ± 8.9) 17/7 16/3 10/24
ICG 8.2 ± 7.3
N/A
ICG 6.4 ± 4.2
Xiao L/China/Surg Endosc (2015) [24] 2010–2012 RM 41 (52.07 ± 11.62) 86 (50.28 ± 11.89) 34/7 77/9 33/41 72/86
Komatsu S/France/Surg Endosc (2016) [25] 2000–2014 RM 38 (61.5 ± 12.2) 38 (61.7 ± 16.1) 34/4 33/5 31/7 28/10
Zhang Y/China/Surg Laparosc Endosc Percutan Tech (2016) [26] 2012–2014 RM 20 (47 ± 8.5) 25 (52 ± 10.5) 12/8 15/10 20/0 25/0
Chen JH/China/Medicine (2017) [27] 2015–2016 RM 126 (51, 21–76) 133 (51, 12–74) 93/33 108/25 ICGR15 4.8 ± 3.8 ICGR15 4.3 ± 4.8
Yoon YI/Korea/Ann Surg (2017) [28] 2007–2015 RM 37 (55.19 ± 7.12) 115 (58.37 ± 9.89) 26/11 93/22 ICGR15 11.6 ± 4.72 ICGR15 13.67 ± 5.51
Guro H/Korea/Surg Oncol (2018) [29] 2004–2015 RM 67 (57.7 ± 11.1) 110 (59.11 ± 12.3) 49/18 93/17 ICGR15 9.1 ± 8.3 ICGR15 9.5 ± 5.9
Rhu J/Korea/World J Surg (2018) [30] 2009–2016 RM 58 (58.2 ± 8.8) 133 (57.9 ± 9.7) 46/12 114/19 ICGR15 11.7 ± 5.4 ICGR15 11.0 ± 4.0
Xu H/China/Surg Endosc (2018) [31] 2015–2017 RM 36 (53.5 ± 11.0) 67 (49.0 ± 13) 30/6 61/6 ICGR15 4.8 ± 2.2 ICGR15 4.9 ± 2.1
  1. Variables are expressed as mean ± SD or no. (%), unless otherwise indicated
  2. Abbreviations: LMLR laparoscopic major liver resection, OMLR open major liver resection, ICGR15 indocyanine green retention rate at 15 min, R retrospective, RM retrospective matched