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Table 1 Characteristics of Studies Included

From: Laparoscopic versus open major liver resection for hepatocellular carcinoma: systematic review and meta-analysis of comparative cohort studies

Reference/Country/Journal (year)

Study Period (year)

Study type

Sample Size (n, y)

Sex ratio (M/F)

Cirrhosis (y/n), or ICGR15

LMLR

OMLR

LMLR

OMLR

LMLR

OMLR

Cho JY/Korea/ Surgery(2015) [23]

2003–2012

R

24 (53.9 ± 12.6)

19 (60.0 ± 8.9)

17/7

16/3

10/24

ICG 8.2 ± 7.3

N/A

ICG 6.4 ± 4.2

Xiao L/China/Surg Endosc (2015) [24]

2010–2012

RM

41 (52.07 ± 11.62)

86 (50.28 ± 11.89)

34/7

77/9

33/41

72/86

Komatsu S/France/Surg Endosc (2016) [25]

2000–2014

RM

38 (61.5 ± 12.2)

38 (61.7 ± 16.1)

34/4

33/5

31/7

28/10

Zhang Y/China/Surg Laparosc Endosc Percutan Tech (2016) [26]

2012–2014

RM

20 (47 ± 8.5)

25 (52 ± 10.5)

12/8

15/10

20/0

25/0

Chen JH/China/Medicine (2017) [27]

2015–2016

RM

126 (51, 21–76)

133 (51, 12–74)

93/33

108/25

ICGR15 4.8 ± 3.8

ICGR15 4.3 ± 4.8

Yoon YI/Korea/Ann Surg (2017) [28]

2007–2015

RM

37 (55.19 ± 7.12)

115 (58.37 ± 9.89)

26/11

93/22

ICGR15 11.6 ± 4.72

ICGR15 13.67 ± 5.51

Guro H/Korea/Surg Oncol (2018) [29]

2004–2015

RM

67 (57.7 ± 11.1)

110 (59.11 ± 12.3)

49/18

93/17

ICGR15 9.1 ± 8.3

ICGR15 9.5 ± 5.9

Rhu J/Korea/World J Surg (2018) [30]

2009–2016

RM

58 (58.2 ± 8.8)

133 (57.9 ± 9.7)

46/12

114/19

ICGR15 11.7 ± 5.4

ICGR15 11.0 ± 4.0

Xu H/China/Surg Endosc (2018) [31]

2015–2017

RM

36 (53.5 ± 11.0)

67 (49.0 ± 13)

30/6

61/6

ICGR15 4.8 ± 2.2

ICGR15 4.9 ± 2.1

  1. Variables are expressed as mean ± SD or no. (%), unless otherwise indicated
  2. Abbreviations: LMLR laparoscopic major liver resection, OMLR open major liver resection, ICGR15 indocyanine green retention rate at 15 min, R retrospective, RM retrospective matched