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Table 3 Clinical and Biological toxicity

From: Systemic high-dose intravenous methotrexate in patients with central nervous system metastatic breast cancer

Toxicity grade 3–4 N %
Clinical Stomatitis 2 9
Biological Elevated serum hepatic transaminases 4 18
Thombocytopenia 3 13.5
Neutropenia 3 13.5
Anemia 1 4.5
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