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Table 2 Association of each index with overall survival

From: Controlling nutritional status (CONUT) score as a preoperative risk assessment index for older patients with colorectal cancer

Variable

Unadjusted

Adjusteda

HR

95% CI

p value

HR

95% CI

p value

CONUT score

 0/1

Ref

–

–

Ref

–

–

 2/3

1.38

1.03–1.85

0.033

1.35

1.00–1.81

0.048

 ≥ 4

2.70

1.82–3.91

<  0.001

2.24

1.48–3.30

<  0.001

ASA-PS

 1

Ref

–

–

Ref

–

–

 2

1.23

0.81–1.94

0.34

1.23

0.81–1.95

0.337

 3

2.08

1.31–3.42

0.002

2.24

1.39–3.70

0.001

CCI

 2

Ref

–

–

Ref

–

–

 3

1.91

1.35–2.67

<  0.001

1.62

1.14–2.28

0.008

 ≥ 4

4.98

3.68–6.72

<  0.001

3.05

2.20–4.24

<  0.001

NIA/NCI

 0/1

Ref

–

–

Ref

–

–

 2/3

1.49

1.13–1.98

0.005

1.29

0.97–1.72

0.085

 ≥ 4

2.03

1.25–3.16

0.005

1.70

1.04–2.69

0.036

ACE-27

 Moderate

Ref

–

–

Ref

–

–

 Severe

2.14

1.64–2.79

<  0.001

1.80

1.37–2.37

<  0.001

  1. CONUT Controlling Nutritional Status, ASA-PS American Society of Anesthesiologists Physical Status classification, CCI Charlson Comorbidity Index, NIA/NCI National Institute on Aging and National Cancer Institute Comorbidity Index, ACE-27 Adult Comorbidity Evaluation-27, HR hazard ratio, CI confidence interval
  2. aHazard ratios adjusted for sex, BMI, lymph node metastasis, Stage, CEA, and CA19–9