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Table 2 Association of each index with overall survival

From: Controlling nutritional status (CONUT) score as a preoperative risk assessment index for older patients with colorectal cancer

Variable Unadjusted Adjusteda
HR 95% CI p value HR 95% CI p value
CONUT score
 0/1 Ref Ref
 2/3 1.38 1.03–1.85 0.033 1.35 1.00–1.81 0.048
 ≥ 4 2.70 1.82–3.91 <  0.001 2.24 1.48–3.30 <  0.001
ASA-PS
 1 Ref Ref
 2 1.23 0.81–1.94 0.34 1.23 0.81–1.95 0.337
 3 2.08 1.31–3.42 0.002 2.24 1.39–3.70 0.001
CCI
 2 Ref Ref
 3 1.91 1.35–2.67 <  0.001 1.62 1.14–2.28 0.008
 ≥ 4 4.98 3.68–6.72 <  0.001 3.05 2.20–4.24 <  0.001
NIA/NCI
 0/1 Ref Ref
 2/3 1.49 1.13–1.98 0.005 1.29 0.97–1.72 0.085
 ≥ 4 2.03 1.25–3.16 0.005 1.70 1.04–2.69 0.036
ACE-27
 Moderate Ref Ref
 Severe 2.14 1.64–2.79 <  0.001 1.80 1.37–2.37 <  0.001
  1. CONUT Controlling Nutritional Status, ASA-PS American Society of Anesthesiologists Physical Status classification, CCI Charlson Comorbidity Index, NIA/NCI National Institute on Aging and National Cancer Institute Comorbidity Index, ACE-27 Adult Comorbidity Evaluation-27, HR hazard ratio, CI confidence interval
  2. aHazard ratios adjusted for sex, BMI, lymph node metastasis, Stage, CEA, and CA19–9