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Table 1 Differential positive immunohistochemical markers in CCSK and other undifferentiated renal neoplasm [1, 22, 42,43,44,45,46,47,48,49]

From: Clear cell sarcoma of the kidney in a 62-year-old patient presenting with generalized pruritus

Undifferentiated renal neoplasm

Positive markers

CCSK

vimentin, CD56

Blastema-predominant Wilms’ tumor

vimentin, NSE, desmin, WT1, cytokeratin cocktail CK22

PNET

CD99, NSE, vimentin, S100, synaptophysin, CD57

MRTK

Vimentin, cytokeratin, EMA, S100, NSE, synaptophysin, CD57

Cellular CMN

vimentin, desmin, muscle actin (HHF-35), alpha Smooth muscle Actin

  1. CCSK clear cell sarcoma of the kidney, PNET primitive neuroectodermal tumor, MRTK malignant rhabdoid tumor of kidney, CMN congenital mesoblastic nephroma, EMA epithelial membrane antigen, NSE neurone specific enolas