Table 2 Multivariate Cox regression analyses of potential prognostic factors for OS and PFS
Variables | OS | PFS | ||
|---|---|---|---|---|
HR(95%CI) | P | HR(95%CI) | P | |
Age | ||||
 ≤ 60 years/>60 years | 0.987 (0.674–1.444) | 0.946 | 0.835 (0.562–1.241) | 0.373 |
ECOG-PS | ||||
 1/>1 | 1.126 (0.725–1.749) | 0.596 | 1.037 (0.668–1.610) | 0.872 |
Extranodal sites | ||||
 ≤ 1/>1 | 1.019 (0.610–1.705) | 0.941 | 1.038 (0.621–1.733) | 0.888 |
Ann Arbor stage | ||||
 IorII/IIIorIV | 1.620 (1.006–2.606) | 0.047 | 1.862 (1.157–2.995) | 0.010 |
LDH | ||||
 ≤ normal/> normal | 1.881 (1.214–2.916) | 0.005 | 1.815 (1.173–2.810) | 0.007 |
IPI score | ||||
 0–2/3–5 | 1.167 (0.562–2.424) | 0.679 | 1.320 (0.631–2.760) | 0.461 |
AMC | ||||
 <460/ul/≥460/ul | 1.658 (1.124–2.446) | 0.011 | 1.675 (1.142–2.457) | 0.008 |
Treatment | ||||
 R-CHOP/CHOP | 1.978 (1.269–3.082) | 0.003 | 1.780 (1.149–2.756) | 0.010 |
CD68 | ||||
 low/high | 1.237 (0.710–2.156) | 0.453 | 1.369 (0.789–2.376) | 0.264 |
CD163 | ||||
 low/high | 2.265 (1.280–4.008) | 0.005 | 1.925 (1.125–3.291) | 0.017 |