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Table 4: Orthotopic injections in NOD/SCID/IL2Rcc-null mice

From: GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma

Cell line Number of cells engrafted Treatments Primary Tumor Volume (mm3) Metastases
Liver Lung
SK-N-DZ 1 000 000 Control 3 559 5/5 5/5
GX 15-070 1 630 1/5 5/5
GX 15-070 + HCQa 540 0/5 0/5
  1. aHCQ: Hydroxychloroquine
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