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Table 3 IC50 of NB cell lines treated with GX 15–070 and doxorubicin

From: GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma

NB cell lines

IC50 (μM)

IC50 (μM)

IC50 (μM)

Doxa

Doxa + 0,05 μM GX 15–070

Doxa + 0,5 μM GX 15–070

SK-N-DZ

0,110

0,002

3283a10− 4

IGR-NB8

1183

0,982

8565a10 − 11

  1. aDox doxorubicin