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Table 3 IC50 of NB cell lines treated with GX 15–070 and doxorubicin

From: GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma

NB cell lines IC50 (μM) IC50 (μM) IC50 (μM)
Doxa Doxa + 0,05 μM GX 15–070 Doxa + 0,5 μM GX 15–070
SK-N-DZ 0,110 0,002 3283a10− 4
IGR-NB8 1183 0,982 8565a10 − 11
  1. aDox doxorubicin
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