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Fig. 5 | BMC Cancer

Fig. 5

From: CSB affected on the sensitivity of lung cancer cells to platinum-based drugs through the global decrease of let-7 and miR-29

Fig. 5

CSB activity is regulated by endogenous let-7 and miR-29. a Relative fluorescence ratio in cells transfected with WT, MT-let-7 and MT-miR-29 constructs respectively. b Relative fluorescence ratio in A549 cells co-transfected with WT and let-7 sponge (let-7-sp) miR-29 sponge (miR-29-sp) or CXCR4 sponge (CXCR4-sp) constructs. Values are normalized to CXCR4-sp construct. **P < 0.01, ***P < 0.001. c Immunoblot for CSB in H2030 cells infected with lentiviral let-7f-1 and miR-29a pri-miRNAs

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BMC Cancer

ISSN: 1471-2407

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