Fig. 3From: CSB affected on the sensitivity of lung cancer cells to platinum-based drugs through the global decrease of let-7 and miR-29ERCC6 gene expresses the longest known CSB-3′UTR isoform in NSCLC. a Schematic of human CSB 3′UTR-APA (alternative polyadenylation), indicating poly(A) sites (red strip) and their approximate location. Specific qPCR strategy amplifying five distinct CSB 3′UTR isoforms used in P1-P5 primer pairs. b qPCR analysis of distinct CSB 3′UTR isoforms levels in A549, H1975 and H2030 cells. Values are normalized to GAPDH. Mean of two independent experiments shownBack to article page