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Fig. 3 | BMC Cancer

Fig. 3

From: CSB affected on the sensitivity of lung cancer cells to platinum-based drugs through the global decrease of let-7 and miR-29

Fig. 3

ERCC6 gene expresses the longest known CSB-3′UTR isoform in NSCLC. a Schematic of human CSB 3′UTR-APA (alternative polyadenylation), indicating poly(A) sites (red strip) and their approximate location. Specific qPCR strategy amplifying five distinct CSB 3′UTR isoforms used in P1-P5 primer pairs. b qPCR analysis of distinct CSB 3′UTR isoforms levels in A549, H1975 and H2030 cells. Values are normalized to GAPDH. Mean of two independent experiments shown

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