Fig. 8

Mice T-47D tumors overexpressing lncE/BC200 and histological sectioning. a Tumors dissected from each mice at 4 weeks. b Representative H&E stained section of poorly differentiated tumor at end point (4 weeks) (40x magnification). The tumor has invaded to the muscle (squared section). c Percent tumor growth at end point. **p.value < 0.01. lncE: lncEPCAM. a shows the dissected tumors at end point for T-47D. H&E staining of poorly differentiated adenocarcinoma is shown in b. Results in c are expressed as percentage tumor growth as two separate experiments’ results were combined to increase the power. Mice containing T-47D-lncEPCAM cells in the mammary fat pad (c), grow significantly larger tumors compared to T-47D-GFP in the 4-week period of the experiment