The diversity between curatively resected pancreatic head and body-tail cancers based on the 8th edition of AJCC staging system: a multicenter cohort study

Table 2 Clinical significance between ph and pbt cancers in 351 cases PC patients with curatively resection

Parameters	No. of patients	Chi square		P	Multivariate analysis Odds ratio (95% CI)	P
Parameters	No. of patients	Head Body-tail		P	Multivariate analysis Odds ratio (95% CI)	P
Cases	351
Age (years)
≤ 65	240	157	83	0.125
> 65	111	63	48
Gender
Male	210	131	79	0.911
Female	141	89	52
Tumor size (cm)
< 2	35	28	7	0.027
≥ 2	316	192	124
Tumor size (cm)
< 3	108	84	24	0.000	2.133(1.180–3.856)	0.012
≥ 3	243	136	107
Differentiation
Well	140	86	54	0.793
Moderate	118	73	45
poor	93	61	32
Lymph nodes metastasis
N0	244	155	89	0.101
N1	91	59	32
N2	16	6	10
7th T stage^a
T1 + T2	242	159	83	0.114
T3	103	58	45
7th AJCC stage^b				0.360
IA	19	13	6
IB	140	86	54
IIA	76	45	31
IIB	104	71	33
IV	6	2	4
8th T stage
T1 + T2	202	140	62	0.003	1.344(0.805–2.243)	0.258
T3 + T4	149	80	69
8th AJCC stage				0.000
IA	24	18	6
IB	119	84	35
IIA	93	42	51
IIB	86	66	20
III	23	8	15
IV	6	2	4
8th AJCC stage
I + II	321	209	112	0.002	2.520(1.121–5.665)	0.025
III + IV	30	11	19
Perineural invasion
Absent	278	180	98	0.118
Present	73	40	33
Vascular permeation
Absent	266	172	94	0.174
Present	85	48	37
Pre-therapeutic CA19–9 level
Mean ± SD	/	389.6 ± 255.7	324.2 ± 283.3	0.429
PLM
Absent	227	156	71	0.002	1.854(1.160–2.963)	0.010
Present	124	64	60

N1 Lymph nodes metastasis 1–3; N2 Lymph nodes metastasis> 3; PLM postoperative live metastasis; 7th and 8th AJCC stage 7th and 8th edition of AJCC staging system in PC; Ph Pancreatic head; Pbt Pancreatic body-tail. a, b 6 cases of T4 stage in 8th TNM stage (III) were exclude

ISSN: 1471-2407