| Median Survival (MS-months) | N | Multivariate analysisa | ||
---|---|---|---|---|---|
Hazard ratio | 95% Cl | p-Value | |||
GBM IDH-wildtype | |||||
CRT | 16.0 | 104 | 0.053 | 0.029â0.098 | <â0.001 |
RT | 6.0 | 104 | 0.181 | 0.105â0.314 | <â0.001 |
None | 2.0 | 18 | Â | Reference | Â |
RT | |||||
âPTEN | |||||
ââDeleted | 7.0 | 74 | 0.74 | 0.45â1.24 | 0.258 |
ââNon-deleted | 6.0 | 20 | Â | Reference | Â |
âMGMT | |||||
ââMethylated | 7.0 | 24 | 1.09 | 0.67â1.78 | 0.733 |
ââUnmethylated | 6.0 | 70 | Â | Reference | Â |
âEGFR | |||||
ââAmplified | 9.0 | 39 | 0.56 | 0.36â0.88 | 0.011 |
ââNon-amplified | 6.0 | 55 | Â | Reference | Â |
CRT | |||||
âPTEN | |||||
ââDeleted | 14.0 | 84 | 1.68 | 0.40â7.15 | 0.481 |
ââNon-deleted | 14.0 | 5 | Â | Reference | Â |
âMGMT | |||||
ââMethylated | 32.0 | 20 | 0.34 | 0.17â0.69 | 0.003 |
ââUnmethylated | 14.0 | 69 | Â | Reference | Â |
EGFR | |||||
ââAmplified | 15.0 | 32 | 0.88 | 0.54â1.43 | 0.596 |
ââNon-amplified | 14.0 | 57 | Â | Reference | Â |