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Table 2 Summary of the treatment and outcome

From: Treatment and outcome of the patients with rhabdomyosarcoma of the biliary tree: Experience of the Cooperative Weichteilsarkom Studiengruppe (CWS)

ID

Study

Primary surgery (IRS)

Secondary surgery

CT

Response

RT (Gy)

Relapse

Outcome

1

CWS-96

Resection (R2, III)

Re-resection (R1)

VAIA

PTR

30.4

LR

DOD

2

CWS-96

Resection (R2, III)

Re-resection (R1)

VAIA

PTR

44.8

 

NED

3

CWS-96

Open biopsy (R2, III)

Resection (R0)

CEVAIE Trofosfamid/VP16 Trofosfamid/Idarubicin SCT

SD

  

NED

4

CWS-96

Resection (R2, III)

 

VAIA/VACA

PTR

39.6

 

NED

5

CWS-96

ERCP biopsy (R2, III)

 

CEVAIE + maintenance therapy Vinblastin/Cyclofosfamide

CR

  

NED

6

CWS-96

Open biopsy (R2, III)

 

VAIA

GR

24

LR

NED

7

CWS-96

Resection (R1, II)

 

VAIA

PTR

36

LR

NED

8

CWS-96

Open biopsy (R2, III)

Resection (R1)

VAIA

PR

32.4

 

NED

9

CWS-96

Open biopsy (R2, III)

 

CEVAIE + SCT

CR

44

CR

DOD

10

CWS-96

Open biopsy (R2, III)

 

CEVAIE + OTIE

PD

 

PD

DOD

11

CWS-2002P

Open biopsy (R2, III)

 

VAIA

GR

30.6

 

NED

12

CWS-2002P

ERCP biopsy (R2, III)

Resection (R0)

I2VA

GR

 

CR

DOD

13

CWS-2002P

Open biopsy (R2, III)

Resection (R0)

VAIA

Nos

 

LR

DOD

14

SoTiSaR

Open biopsy (R2, III)

Resection (R0)

CEVAIE

SD

  

NED

15

SoTiSaR

ERCP biopsy (R2, III)

Resection (R0)

CEVAIE+OTIE

CR

  

NED

16

SoTiSaR

Resection (R0, I)

 

VA

PTR

  

NED

17

SoTiSaR

Open biopsy (R2, III)

 

CEVAIE + OTIE

PD

 

PD

DOD

  1. CEVAIE ifosfamid, carboplatine, epirubicine, vincristine, dactinomycin, etoposide, CR complete response, CT chemotherapy, DOD dead of disease, ERCP endoscopic retrograde cholangiopacreatography, GR good response, Gy gray, I2VA ifosfamide, vincristine, dactinomycin, NED no evidence of disease, Nos not otherwise specified, O-TIE oral maintenance therapy – trofosfamide, idarubicine, etoposide, PD progressive disease, PR poor response, PTR primary tumor resection, RT radiotherapy, SCT stem cell transplantation, SD stable disease, VA vincristine, actinomycin, VAIA ifosfamide, vincristine, adriamycin, dactinomycin, VP16 etoposide