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Table 2 Age, stage, Gleason score and treatment received for PSA-detected compared to symptomatic prostate cancer survivors#

From: Quality of life among symptomatic compared to PSA-detected prostate cancer survivors - results from a UK wide patient-reported outcomes study

Respondent characteristics Proportion PSA-detected a
(n = 11,210)
Proportion symptomatic a
(n = 21,378)
Adjusted odds ratio (95% CI) of being symptomatic compared to PSA-detected b
(n = 32,588)
All respondents (n = 32,588) 34.4% 65.6%
Age at diagnosis
  < 54 36.3% 63.7% 1.00
 55-64 35.0% 65.0% 0.92 (0.81-1.05)
 65-74 35.3% 64.7% 0.83 (0.72-0.95)*
 75+ 31.8% 68.2% 0.87 (0.75-1.01)
Stage
 I/II 38.3% 61.7% 1.00
 III 32.2% 67.8% 1.20 (1.12-1.28)**
 IV 18.5% 81.5% 2.03 (1.82-2.27)**
Gleason score
 2-6 37.0% 63.0% 1.00
 7 37.3% 62.7% 0.86 (0.80-0.92)**
 8-10 25.4% 74.6% 1.12 (1.03-1.22)*
Treatment type c
 Any surgery 36.7% 63.3% 1.05 (0.98-1.13)
 Any EBRT 32.7% 67.3% 1.04 (0.98-1.11)
 Any brachytherapy 42.4% 57.6% 0.77 (0.70-0.85)**
 Any ADT 29.4% 70.6% 1.22 (1.14-1.30)**
 Any systemic 17.7% 82.3% 1.64 (1.43-1.89)**
 Any other 37.1% 62.9% 1.00 (0.92-1.09)
 Monitoring only 37.4% 62.6% 1.05 (0.96-1.16)
  1. Notes
  2. EBRT External Beam Radiotherapy, ADT Androgen Deprivation Therapy, Systemic - Chemotherapy/Abiraterone/Enzalutamide # Alive 18-42 months after diagnosis, CI: Confidence interval
  3. * p < 0.05, ** p < 0.001
  4. a Denominator excludes other and missing method of presentation
  5. b Determined using multivariable logistic regression adjusted for other variables in the table plus nation, deprivation, number of comorbidities, BMI, ethnicity, marital status and employment status. An odds ratio greater than 1 represents a greater odds than the baseline (i.e. first) group of being symptomatic compared to PSA-detected
  6. c Men may have more than one type of treatment. Odds ratios for treatment type have a reference category of not receiving that treatment type (i.e. No surgery, No EBRT etc.)