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Fig. 7 | BMC Cancer

Fig. 7

From: Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling

Fig. 7

Effect of Tadalafil upon various inflammatory and apoptotic markers. Groups are defined as: Control (Normal saline, 3 ml/kg, p.o.); Toxic control (MNU 47 mg/kg, i.v.); MNU + Tadalafil (47 mg/kg i.v. + 2 mg/kg p.o.) and MNU + Tadalafil (47 mg/kg i.v. + 4 mg/kg p.o.).Values were expressed as mean ± SD. Comparisons were made on the basis of one-way ANOVA followed by Bonferroni multiple test and all groups are compared to the toxic control group (*p < 0.05, **p < 0.01, ***p < 0.001)

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