irAEs | No. (%) | Median days to onset | Grade of irAEs, n, 1/2/3/4 |
---|---|---|---|
Diarrhea/colitis | 5 (7.7) | 60.0 | 2/2/1/0 |
Hyperglycemia | 2 (3.1) | 398.5 | 0/0/2/0 |
Pruritus | 2 (3.1) | 50.0 | 2/0/0/0 |
Rash | 2 (3.1) | 12.0 | 1/1/0/0 |
Type 1 DM | 2 (3.1) | 398.5 | 0/2/0/0 |
Adrenal insufficiency | 1 (1.5) | 143.0 | 0/0/1/0 |
ALT increased | 1 (1.5) | 28.0 | 0/1/0/0 |
AST increased | 1 (1.5) | 28.0 | 0/0/1/0 |
Appetite loss | 1 (1.5) | 158.0 | 1/0/0/0 |
Hypothyroidism | 1 (1.5) | 167.0 | 1/0/0/0 |
Dry skin | 1 (1.5) | 29.0 | 1/0/0/0 |
Edema limbs | 1 (1.5) | 28.0 | 1/0/0/0 |
Myalgia | 1 (1.5) | 16.0 | 0/1/0/0 |
Peripheral motor neuropathy | 1 (1.5) | 3.0 | 0/0/1/0 |
Pneumonitis | 1 (1.5) | 32.0 | 0/1/0/0 |
QTc interval prolonged | 1 (1.5) | 42.0 | 1/0/0/0 |