Fig. 3From: Screening antiproliferative drug for breast cancer from bisbenzylisoquinoline alkaloid tetrandrine and fangchinoline derivatives by targeting BLM helicaseEffects of HJNO or MMC on DNA unwinding of BLM helicase. aThe effects of HJNO on DNA unwinding of BLM helicase. b The effects of 1.67, 6.67, 13.34 and 50 μmol/L HJNO on DNA unwinding time curve of BLM helicase. c The effects of MMC on DNA unwinding of BLM helicase; d The effects of 0.2, 2 and 2.7 μmol/L MMC on DNA unwinding time curve of BLM helicase. Note: A1 is the fluorescence anisotrophy of BLM binding DNA and small molecules. A2 is the fluorescence anisotrophy after adding 0.2 mmol/L ATPBack to article page