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Table 3 Comparison of patients’characteristics at diagnosis in BCR-ABL1 positive ALL with complex and single patterns

From: Heterogeneous BCR-ABL1 signal patterns identified by fluorescence in situ hybridization are associated with leukemic clonal evolution and poorer prognosis in BCR-ABL1 positive leukemia

Characteristics

Complex patterns

Single pattern

P value

Number of patients

16

36

 

Median Age, y (Range)

38.3 (16–61)

39.0 (13–76)

0.945

Male/Female, %

43.8/56.3

57.7/42.3

0.124

Leukocyte count, 109/L (range)

41.4 (1.2–106)

57.4 (1.1–308)

0.753

Hemoglobin, g/L (range)

84.9 (38–127)

87.3 (38–149)

0.784

Thrombocyte count, 109/L (range)

47.8 (7–230)

43.0 (3–230)

0.753

LDH, U/L (range)

978 (250–5353)

766 (156–3723)

0.364

Cytogenetic abnormalities, %

  

0.379

 t (9;22)

2/16 (12.5%)

9/36 (25.0%)

 

 ACAs

5/16 (31.3%)

6/36 (16.7%)

 

 No split phase

9/16 (56.3%)

21/36 (58.3%)