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Table 1 Clinicopathological characteristics of cohort. Fisher’s exact test and Chi-square test (as appropriate) were used to generate P-values

From: Stromal ColXα1 expression correlates with tumor-infiltrating lymphocytes and predicts adjuvant therapy outcome in ER-positive/HER2-positive breast cancer

Characteristic

No.

ColXα1 Positive N (%)

P-value

No. of patients

164

62.8%

 

Age (year)

164

 

  < 65

99

57 (57.5%)

0.10

  ≥ 65

65

46 (71%)

 

Age (year)

  < 58

 

61%

0.75

  ≥ 58

 

64%

 

Laterality

164

 

 Left

94

54 (57.3%)

0.52

 Right

70

30 (42.7%)

 

Foci

164

 

 Solitary

146

61.6%

0.45

 Multifocal

18

72.2%

 

LVI

130

 

 Pos

97

62 (63.9%)

0.005

 Neg

33

21 (63.6%)

 

Lymph node status

120

 

0.21

 N0

64

30 (46.9%)

 

 N1

42

26 (61.9%)

 

 N2

8

4 (50.0%)

 

 N3

6

5 (83.3%)

 

Clinical stage

164

 

 I

52

61.5%

0.34

 II

87

60.9%

 

 III

22

77.3%

 

 IV

3

33.3%

 

ColXα1

164

 

 0

21

 

 1

40

  

 2

47

  

3

56

  

Stroma Content

164

 

 0

30

15 (50%)

0.024

1

95

57 (60%)

 

 2

39

31 (79.5%)

 

TILs

164

 

 1 (Rare)

22

15 (68.2%)

< 0.001

 2 (Low density)

113

82 (72.6%)

 

 3 (High density)

29

6 (20.7%)