Fig. 1

The locations of rs2273535, rs1047972, rs911160 and rs8173 polymorphisms in AURKA, rs2241909 and rs2289590 in AURKB, rs758099 and rs11084490 in AURKC and rs42873 in PLK1 mitotic checkpoint genes. White boxes: untranslated regions (UTRs). Orange boxes: protein coding regions. The black lines connecting boxes: introns. The gene structures were extracted from the Research Collaboratory for Structural Bioinformatics (RCSB) Protein Data Bank (PDB), GRCh38 Genome Assembly