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Table 1 Patient and tumor characteristics included in primary retinoblastoma cohort

From: CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing

Patients

Total

CD171 positive*

CD171 negative

N (%)

30 (100)

15 (50)

15 (50)

Minimum age at diagnosis (years)

0.1

0.4

0.1

Maximum age at diagnosis (years)

6.5

6.4

6.5

Median age at diagnosis (years)

2.1 (0.12–6.5)

1.8

2.1

Sex (%)

♀: 15 (50)

♀:9 (60)

♀:6 (40)

♂: 15 (50)

♂:6 (40)

♂:9 (60)

Unilateral (%)

23 (77)

12 (80)

11 (73)

Bilateral (%)

7 (23)

3 (20)

4 (27)

ICRB (%)

 A

0 (0)

0 (0)

0 (0)

 B

0 (0)

0 (0)

0 (0)

 C

1 (3)

1 (7)

0 (0)

 D

17 (57)

9 (60)

7 (47)

 E

7 (20)

3 (20)

4 (26)

 n.a.

6 (20)

2 (13)

4 (26)

  1. * ≥ 5% CD171 positive cells, N = number, ICRB = International Classification of Retinoblastoma