LETM1 expression is correlated with unfavorable progression of non-small cell lung carcinoma (NSCLC). a Oncomine mRNA analysis of LETM1 expression in normal and NSCLC (www.oncomine.org) samples. b Kaplan-Meier analysis showed overall survival rate of NSCLC patients with LETM1 expression. c Immunohistochemical double staining for LETM1/CD105 in NSCLC. LETM1 (brown) is expressed in the cancer cells, and CD105 (red) is expressed in new capillary blood vessels around cancer cells in the host (100×). d Graphs showing the microvessel density (MVD) between LETM1 positive and negative groups in NSCLC.