Fig. 5
From: Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression
L1 reduces AMOG expression and suppresses apoptosis . Western blot analysis of L1 and AMOG (a, e, i), phosphorylation levels of Akt1 (b, f, j) and Erk1/2 (c, g, k), and ratio of Bcl-2/Bax (d, h, l) in U-87 MG, U251 and SHG44 cells after treatment with recombinant L1 (rL1) at concentrations between 0 to 10 nM. Mean values ± SEM are from 4 independent experiments; one-way ANOVA with Tukey’s post-hoc test. *p < 0.05, **p < 0.01, and ***p < 0.001 versus the Control siRNA group