Table 1 Correlation between TIL, TAM and clinicopathologic characteristics in the 401 gastric cancers
Characteristics | CD8+ TIL | p value | CD68+ TAM | p value | ||
|---|---|---|---|---|---|---|
Negative (%) | Positive (%) | Negative (%) | Positive (%) | |||
All cases | 196 (48.6) | 205 (51.1) | Â | 217 (54.1) | 184 (45.9) | Â |
Sex | Â | Â | 0.596 | Â | Â | Â |
 Female | 61 (31.1) | 69 (33.7) |  | 72 (33.2) | 58 (31.5) | 0.749 |
 Male | 135 (68.9) | 136 (68.3) |  | 145 (66.8) | 126 (68.5) |  |
Age (y) | Â | Â | 0.915 | Â | Â | 0.668 |
 <65 | 134 (68.4) | 139 (67.8) |  | 150 (69.1) | 123 (66.8) |  |
  ≥ 65 | 62 (31.6) | 66 (32.2) |  | 67 (30.9) | 61 (33.2) |  |
Tumor location | Â | Â | 0.805 | Â | Â | 0.330 |
 Proximal | 58 (29.6) | 59 (28.8) |  | 68 (31.3) | 49 (26.6) |  |
 Middle | 30 (15.3) | 39 (19.0) |  | 37 (17.1) | 32 (17.4) |  |
 Distal | 96 (49.0) | 95 (46.3) |  | 103 (47.5) | 88 (47.8) |  |
 Entire | 12 (6.1) | 12 (5.9) |  | 9 (4.1) | 15 (8.2) |  |
Tumor size (cm) | Â | Â | 0.260 | Â | Â | 0.441 |
 <5 | 114 (58.2) | 131 (63.9) |  | 137 (63.1) | 108 (58.7) |  |
  ≥ 5 | 82 (41.8) | 74 (36.1) |  | 80 (36.9) | 76 (41.3) |  |
Differentiation | Â | Â | 0.858 | Â | Â | 0.840 |
 Differentiated | 83 (42.3) | 85 (41.5) |  | 92 (42.4) | 76 (41.3) |  |
 Undifferentiated | 113 (57.7) | 120 (58.5) |  | 125 (57.6) | 108 (58.7) |  |
Lymphovascular invasion | Â | Â | 0.044 | Â | Â | 0.130 |
 Absent | 101 (51.5) | 127 (62.0) |  | 131 (60.4) | 97 (52.7) |  |
 Present | 95 (48.5) | 78 (38.0) |  | 86 (39.6) | 87 (47.3) |  |
Tumor depth | Â | Â | 0.158 | Â | Â | 0.225 |
 T1/2 | 75 (38.3) | 93 (45.4) |  | 97 (44.7) | 71 (38.6) |  |
 T3/4 | 121 (61.7) | 112 (54.6) |  | 120 (55.3) | 113 (61.4) |  |
Lymph node metastasis | Â | Â | 0.014 | Â | Â | 0.919 |
 Absent | 65 (33.2) | 93 (45.4) |  | 86 (39.6) | 72 (39.1) |  |
 Present | 131 (66.8) | 112 (54.6) |  | 131 (60.4) | 112 (60.9) |  |
Pathological stage | Â | Â | 0.123 | Â | Â | 0.561 |
 I | 57 (29.1) | 78 (38.0) |  | 78 (35.9) | 57 (31.0) |  |
 II | 41 (20.9) | 43 (21.0) |  | 43 (19.8) | 41 (22.3) |  |
 III | 98 (50.0) | 84 (41.0) |  | 96 (44.2) | 86 (46.7) |  |
Adjuvant chemotherapy | Â | Â | 0.222 | Â | Â | 0.917 |
 Absent | 65 (33.2) | 80 (39.0) |  | 79 (36.4) | 66 (35.9) |  |
 Present | 131 (66.8) | 125 (61.0) |  | 138 (63.6) | 118 (64.1) |  |