Fig. 8
From: Circ-SMARCA5 suppresses progression of multiple myeloma by targeting miR-767-5p
Luciferase reporter assay of Circ-SMARCA5. The sequences of wild type Circ-SMARCA5, mutant type Circ-SMARCA5 and miR-767-5p were shown and the binding sites were lined up (a). For wild type Circ-SMARCA5, the relative luciferase activity was decreased in miR-767-5p group compared to miR-NC group, whereas for mutant type Circ-SMARCA5, the relative luciferase activity was similar between miR-767-5p group and miR-NC group (b). Comparison of relative luciferase activity between the two groups was conducted using t test, and P < 0.05 was considered significant. **P < 0.01, NS, non-significant. Circ-SMARCA5, Circular RNA SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; miR, micro RNA