Fig. 1

a-b: Circ-SMARCA5 relative expression in MM patients. Wilcoxon rank sum test was used to compare Circ-SMARCA5 relative expression between MM patients and controls, and the ROC curve was used to evaluate the ability of Circ-SMARCA5 relative expression to discriminate between MM patients and controls. c- d: Association of Circ-SMARCA5 expression with treatment response in MM patients. The cutoff value of Circ-SMARCA5 was the median value of Circ-SMARCA5 in MM patients. Comparison between two groups was performed using the Chi-square test. e- f: Comparison of PFS and OS between Circ-SMARCA5 high expression and low expression groups. The cutoff value of Circ-SMARCA5 was the median value of Circ-SMARCA5 in MM patients. Survival curves were made using the Kaplan-Meier method and differences between the curves were determined by log-rank test. P < 0.05 was considered significant. PFS, progression free survival; OS, overall survival; Circ-SMARCA5, Circular RNA SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; ROC, Receiver operating characteristic. CR, complete response; ORR, objective response rate