Table 1 Association between clinicopathologic features and H. pylori status of 129 patients with de novo gastric diffuse large B-cell lymphoma
From: Prognostic significance of helicobacter pylori-infection in gastric diffuse large B-cell lymphoma
Patients | Number of patients n = 129(%) | H. pylori-negative n = 64 (%) | H. pylori-positive n = 65 (%) | p |
|---|---|---|---|---|
Gender | ||||
Female | 66(51.2) | 39(53.4) | 27(48.2) | 0.557 |
Male | 63(48.8) | 34(46.6) | 29(51.8) | |
Age, years | ||||
< 60 | 73(56.6) | 43(58.9) | 30(53.6) | 0.545 |
≥ 60 | 56(43.4) | 30(41.1) | 26(46.4) | |
Presence of B symptoms | ||||
No | 84(65.1) | 43(58.9) | 41(73.2) | 0.091 |
Yes | 45(34.9) | 30(41.1) | 15(26.8) | |
Tumor sites | ||||
Proximal | 11(13.4) | 7(17.1) | 4(9.8) | 0.331 |
Distal | 71(86.6) | 34(82.9) | 37(90.2) | |
Lugano stage | ||||
I/II | 88(66.7) | 44(60.3) | 44(78.6) | 0.027 |
IIE/IV | 41(33.3) | 29(39.7) | 12(21.4) | |
IPI risk group | ||||
Low (intermediate) risk | 109(84.5) | 57(78.1) | 52(92.9) | 0.022 |
High (intermediate) risk | 20(15.5) | 16(21.9) | 4(7.1) | |
ECOG | ||||
0–1 | 117(90.7) | 65(89.0) | 52(92.9) | 0.460 |
≥ 2 | 12(9.3) | 8(11.0) | 4(7.1) | |
Surgical treatment | ||||
No | 87(67.4) | 43(58.9) | 44(78.6) | 0.018 |
Yes | 42(32.6) | 30(41.1) | 12(21.4) | |
Histological analyses | ||||
non-GCB | 56(70.0) | 28(66.7) | 28(73.7) | 0.494 |
GCB | 24(30.0) | 14(33.3) | 10(26.3) | |
LDH | ||||
< 220 U/L | 92(71.3) | 44(60.3) | 48(85.7) | 0.002 |
≥ 220 U/L | 37(28.7) | 29(39.7) | 8(14.3) | |