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Fig. 2 | BMC Cancer

Fig. 2

From: Generation of dual specific bivalent BiTEs (dbBIspecific T-cell engaging antibodies) for cellular immunotherapy

Fig. 2

Electron microscopy analysis of dbBiTES. a Representative EM of 300 kDa particles at 67,000 magnification. b 2D average reconstruction of > 100 6-lobed particles. IgG lobes arbitrarily labeled as 1–6, the 6th lobe assumed out of the plane (z-axis) of the paper. c 3D reconstruction of 6-lobed particles using tilt beam EM. Lobes labeled as above

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