Fig. 7From: Lipid accumulation impairs natural killer cell cytotoxicity and tumor control in the postoperative periodPostoperative lipid-laden NK cells are dysfunctional against tumor targets. Surgical trauma induces up-regulation of scavenger receptors (SR) MSR1, CD36 and CD68 on postoperative NK cells. NK cells with greater SR expression are associated with increased lipid uptake and accumulation. This leads to impaired NK cell anti-tumor immune response and metastatic spread following cancer surgeryBack to article page