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Table 2 Multivariable Cox regression analysis of overall survival, cancer specific survival, recurrence free survival

From: Clinical outcomes of muscle invasive bladder Cancer according to the BASQ classification

Parameter Overall survival Cancer specific survival Recurrence free survival
HR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value
pT stage
 T2 reference   reference   Reference  
  ≥ T3 1.46 (1.15–1.85) 0.002 1.49 (1.17–1.90) 0.001 2.04 (0.38–10.74) 0.400
LVI 0.86 (0.25–2.93) 0.806 2.33 (0.44–12.16) 0.316 2.66 (0.97–7.65) 0.060
CIS 0.90 (0.28–2.89) 0.858 4.15 (1.21–16.03)) 0.028 0.70 (0.43–1.14) 0.160
N stage   0.478   0.096   0.096
 N0 reference   Reference   reference  
  ≥ N1 1.71 (1.46–1.99) < 0.001 1.75 (1.62–1.91) 0.004 2.96 (1.40–6.22) 0.004
CK5/6 3.30 (0.81–14.63) 0.101 2.57 (0.90–8.16) 0.088 3.15 (0.8–12.63) 0.104
CK14 6.16 (1.28–38.30) 0.033 3.96 (1.13–16.36) 0.040 3.19 (1.07–9.55) 0.037
GATA3 0.77 (0.37–1.58) 0.477 0.81 (0.22–2.89) 0.742 0.29 (0.01–5.27) 0.409
FOXA1 0.08 (0.01–0.59) 0.023 0.08 (0.01–0.61) 0.024 0.12 (0.1–1.51) 0.103
  1. HR Hazard ratio, CI Confidence interval, LVI Lymphovascular invasion, CIS Carcinoma in situ, LND Lymph node dissection, LN Lymph node, UC Urothelial carcinoma