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Fig. 1 | BMC Cancer

Fig. 1

From: The peroxidase PRDX1 inhibits the activated phenotype in mammary fibroblasts through regulating c-Jun N-terminal kinases

Fig. 1

PRDX1-deficient MEFs exhibit characteristics found in myofibroblasts and cancer-associated fibroblasts. a MEFs were analyzed for α-SMA (red), Hoechst nuclear stain (blue) using immunofluorescence. Scale bar is 1 μm. b MEFs were analyzed for α-SMA or FAP and collagen using immunoblotting. c and d Transwell migration and invasion assays in Prdx1−/−MEFs reconstituted with wild-type (WT) PRDX1 protein. Values indicate the mean ± SD for 3 repeats. Individual treatment samples were analyzed for statistical significance by Students t-test

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