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Fig. 5 | BMC Cancer

Fig. 5

From: Reduction of metastatic potential by inhibiting EGFR/Akt/p38/ERK signaling pathway and epithelial-mesenchymal transition after carbon ion exposure is potentiated by PARP-1 inhibition in non-small-cell lung cancer

Fig. 5

Expression of few EMT markers after 12C ion exposure with and without olaparib or siRNA. a Typical western blots of N-cadherin and vimentin in A549 (left) and H1299 (right) cells. b & c Relative expression of N-cadherin and vimentin in A549 and H1299 cells as measured in fold. d, e, f & g Expression of the EMT markers N-cadherin, anillin, claudin-1 and claudin-2 respectively by Real Time PCR after normalizing with GAPDH in A549 cell line. All the differences with respect to control are significant and p-values at each dose were p ≤ 0.001

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