Fig. 1
From: Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer
Oct4, Egr1, and OPN are overexpressed in lung cancer and Egr1 expression is correlated with shorter survival. a, Representative staining for Oct4, Egr1, and OPN in human lung tumors graded as low and high expression. b, Numbers of tumors expressing high or low levels of Egr1 in tumors with high or low Oct4 expression. c. Numbers of tumors expressing high or low levels of OPN in tumors with high or low Egr1 expression. d, Tumor recurrence rates between high- and low- expression of Oct4, Egr1, and OPN in lung cancer patients, none of them reached statistical significance (Oct4: p = 0.273; Egr1: 0.261; OPN: 0.253). e-g, Kaplan-Meier curves for disease-free survivals in patients with high (red line) and low (black line) Oct4 (e), Egr1 (f), and OPN (g) expression