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Table 3 Multivariate analysis of prognostic factors for iPFS in 78 patients

From: Combination therapy of brain radiotherapy and EGFR-TKIs is more effective than TKIs alone for EGFR-mutant lung adenocarcinoma patients with asymptomatic brain metastasis

  P HR 95.0% CI for HR
Lower Upper
Gender (male vs. female) 0.137 0.16 0.02 1.78
Age (<65y vs. ≥65y) 0.890 0.94 0.37 2.34
Smoking history (never vs. smoking) 0.134 5.57 0.59 52.53
EGFR mutation (L858r vs. Del19 vs. rare mutations) 0.665 0.83 0.36 1.91
BM No. (≤3 vs.>3) 0.315 0.63 0.26 1.55
Metastases(B vs. B + E) 0.740 0.82 0.26 2.58
Intracranial symptom (have vs. No) 0.267 0.60 0.24 1.48
First-line treatment (Yes vs. No) 0.445 1.55 0.51 4.74
KPS score (<80% vs ≥80%) 0.918 0.94 0.26 3.37
  1. No. Number, B brain, B + E brain and extracranial metastasis
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