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Fig. 3 | BMC Cancer

Fig. 3

From: Silencing microRNA-330-5p increases MMP1 expression and promotes an invasive phenotype in oesophageal adenocarcinoma

Fig. 3

Protease and protease inhibitor antibody-based array profiles. Silencing miR-330-5p altered the expression of secreted proteases (a) and protease inhibitors (b) in 24 h conditioned media. Densitometry analysis was used to calculate the fold change in protein expression in the OE33 miRZIP-330-5p SC relative to the OE33 miRZIP-VC SC. Highlighted in bold are proteins that exceeded ±1.2 fold change. The antibody-based array confirmed an increase in MMP1 expression with miR-330-5p silencing, and confirmed no increase in MMP7 expression. Data represent a single experimental repeat

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BMC Cancer

ISSN: 1471-2407

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