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Fig. 1 | BMC Cancer

Fig. 1

From: Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants

Fig. 1

Variability in called variants across TCGA sequencing centers. Batch effect due to sequencing center in 1522 samples associated with Caucasian populations (originated in Europe, Middle East or North Africa) across the six analyzed cancer types. a Number of called exome variants per sample. b Ratio of transition-transversion (TITv) variants per sample. Colors represent the genomic sequencing centers: BI (blue), WUGSC (orange) and BCM (green)

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