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Table 3 MAF patterns of BRAF mutant melanoma metastases compared to the primary

From: Dynamic and unpredictable changes in mutant allele fractions of BRAF and NRAS during visceral progression of cutaneous malignant melanoma

  1. Patterns have been derived from Fig. 3. MAF classification: High was characterized by MAF > 40%, Medium referred to MAF of 15–40% while Low was defined as < 15% MAF. p primary tumor, m metastasis, H high, M medium, L low. N number of cases. Gray box = cases where extreme MAF changes (H to L or L to H) detected in individual metastasis