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Table 1 Allowable doses and fractionations*

From: Stereotactic ablative radiotherapy for the comprehensive treatment of 4–10 oligometastatic tumors (SABR-COMET-10): study protocol for a randomized phase III trial

Number of Fractions

Preferred Dose

Acceptable Doses

Major Deviation

1

20 Gy

16–24 Gy

<  16 Gy or > 24 Gy

3

30 Gy

24–33 Gy

<  24 Gy or > 33 Gy

5

35 Gy

25–40 Gy

<  25 Gy or > 40 Gy

  1. *Note that centres should use doses that standard at their institutions based on the specific clinical situation, within these guidelines. For example, if the standard dose for a 2.5 cm brain metastasis is 24 Gy in 3 fractions, which is an ‘acceptable dose’, that should be used instead of the ‘preferred dose’