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Table 3 Univariate and multivariate analyses of prognostic factors for overall survival in AML patients

From: Circ-Foxo3 is positively associated with the Foxo3 gene and leads to better prognosis of acute myeloid leukemia patients

Whole patients

Univariate

Multivariate

HR (95% CI)

Exp.

P value

HR (95% CI)

Exp.

P value

Flt3-ITD

0.575–2.330

1.158

0.681

0.885–2.330

1.435

0.295

NPM1

1.044–5.017

2.289

0.039

0.471–3.644

1.309

0.606

CEBPA

0.515–2.253

1.077

0.843

0.402–3.666

1.215

0.730

WBC count

1.891–4.505

2.918

< 0.001

0.804–2.571

1.437

0.221

Karyotypic classification

1.628–2.763

2.121

< 0.001

1.113–2.188

1.561

0.010

Foxo3 expression

0.499–1.156

0.762

0.210

0.341–0.951

0.569

0.031

Circ-Foxo3 expression

0.650–1.661

1.039

0.873

0.664–2.200

1.208

0.536

Age

2.274–5.538

3.549

< 0.001

1.854–5.523

3.200

< 0.001

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BMC Cancer

ISSN: 1471-2407

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