Table 1 Patients and tumor characteristics (n = 414)
Variable | Value (%) |
|---|---|
Age at diagnosis (yr) | |
Median | 59.7 |
< 50 | 103 (24.9) |
50–65 | 173 (41.8) |
> 65 | 138 (33.3) |
Menopausal status | |
Pre/perimenopausal | 109 (26.3) |
Postmenopausal | 305 (73.7) |
Molecular subtypes | |
Luminal A | 156 (37.7) |
Luminal B | 176 (42.5) |
HER2 | 27 (6.5) |
Triple negative | 55 (13.3) |
Tumour size | |
≤ 2 cm | 272 (65.7) |
> 2 cm | 142 (34.3) |
Histotypes | |
Ductal carcinoma | 330 (79.7) |
Lobular carcinoma | 54 (13.0) |
Other | 30 (7.3) |
Tumour grade | |
1 | 64 (15.5) |
2–3 | 350 (84.5) |
ER | |
Negative | 89 (21.5) |
Positive | 325 (78.5) |
PgR | |
Negative | 188 (45.4) |
Positive | 226 (54.6) |
Ki-67 | |
Low | 287 (69.3) |
High | 127 (30.7) |
HER2 | |
Negative | 348 (84.1) |
Positive | 66 (15.9) |
PLCγ1 | |
Low | 225 (54.3) |
High | 189 (45.7) |
PLCγ1-pY1253 | |
Low | 241 (58.2) |
High | 173 (41.8) |
PLCγ1-pY783 | |
Low | 327 (79.0) |
High | 87 (21.0) |
Patient outcome | |
Without recurrence | 299 (72.2) |
Local recurrence | 50 (12.1) |
Distant recurrence | 65 (15.7) |