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Table 1 Patients and tumor characteristics (n = 414)

From: PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes

VariableValue (%)
Age at diagnosis (yr)
 Median59.7
 < 50103 (24.9)
 50–65173 (41.8)
 > 65138 (33.3)
Menopausal status
 Pre/perimenopausal109 (26.3)
 Postmenopausal305 (73.7)
Molecular subtypes
 Luminal A156 (37.7)
 Luminal B176 (42.5)
 HER227 (6.5)
 Triple negative55 (13.3)
Tumour size
 ≤ 2 cm272 (65.7)
 > 2 cm142 (34.3)
Histotypes
 Ductal carcinoma330 (79.7)
 Lobular carcinoma54 (13.0)
 Other30 (7.3)
Tumour grade
 164 (15.5)
 2–3350 (84.5)
ER
 Negative89 (21.5)
 Positive325 (78.5)
PgR
 Negative188 (45.4)
 Positive226 (54.6)
Ki-67
 Low287 (69.3)
 High127 (30.7)
HER2
 Negative348 (84.1)
 Positive66 (15.9)
PLCγ1
 Low225 (54.3)
 High189 (45.7)
PLCγ1-pY1253
 Low241 (58.2)
 High173 (41.8)
PLCγ1-pY783
 Low327 (79.0)
 High87 (21.0)
Patient outcome
 Without recurrence299 (72.2)
 Local recurrence50 (12.1)
 Distant recurrence65 (15.7)