Fig. 5

PTTG3P/miR-383 axis in the phenotypes of HCC cells. HepG2 and Huh-7 cells were co-transfected with PTTG3 siRNA and miR-383 inhibitor, or corresponding controls, and then subjected to CCK-8 assay to detect the cell viability (a), or to flow cytometry to detect the cell cycle distribution (b), or to Transwell migration (c) and invasion (d) assays to detect the changes in the migratory and invasive abilities of HCC cells. The color code in 5B represented the G1 stage, S stage and G2 stage, respectively (Left to right). The results were shown as mean ± SD from three independent experiments and one of the representative results was shown. Each experiment was performed in triplicate. *P < 0.05