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Table 2 Univariate and multivariate analyses of clinical variables contributing to overall survival

From: MicroRNA-1275 inhibits cell migration and invasion in gastric cancer by regulating vimentin and E-cadherin via JAZF1

Variable

Univariate analysis

Multivariate analysis

HR (95%CI)

p

HR (95%CI)

p

Age (< 60 vs. ≥60)

0.950 (0.568–1.590)

0.846

–

–

Sex (male vs. female)

0.863 (0.372–2.001)

0.731

–

–

Tumor location (Upper or middle vs. Lower stomach)

1.378 (0.474–4.006)

0.556

–

–

Histological differentiation (well or moderate vs. poor)

0.634 (0.329–1.224)

0.175

–

–

Tumor invasion (AJCC) (Tis-T2 vs. T3-T4)

1.512 (0.617–3.708)

0.366

–

–

Lymph node metastasis (yes vs. no)

1.359 (0.592–3.122)

0.043

1.245 (0.519–2.983)

0.623

TNM stage (AJCC) (I-IIvs.III-IV)

1.477 (0.548–3.981)

0.002

1.363 (0.480–3.874)

0.561

Surgery type (curative resection vs. palliative)

1.205 (0.521–2.786)

0.663

–

–

miR-1275 expression in tumor (low vs. high)

0.268(0.154–0.464)

0.001

0.126 (0.035–0.448)

0.001

  1. Bolded values are significant, P < 0.05; CI, Confidence interval; HR, Hazard ratio
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BMC Cancer

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