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Table 5 Univariate and multivariate analyses showing that Pin1/RhoA/RhoC co- overexpression could serve as an independent prognostic factor for recurrence of HCC patients

From: Overexpression of Pin1 and rho signaling partners correlates with metastatic behavior and poor recurrence-free survival of hepatocellular carcinoma patients

  Relative risk (95% confidence interval P-value
Univariate analysis
 Age, year (> 55 versus ≤55) 1.350 (0.802–2.270) 0.258
 Gender (male versus female) 1.041 (0.576–1.881) 0.894
 HBsAg (positive versus negative) 0.820 (0.451–1.489) 0.513
 Cirrhosis (yes versus no) 0.921 (0.565–1.503) 0.743
 Tumor Size (> 5 versus ≤5) 1.576 (0.950–2.614) 0.078
 TNM stage (III to IV versus I to II) 4.857 (2.841–8.303) <0.001
 Pin1 + RhoA/RhoC co-overexpression (yes versus no) 2.804 (1.686–4.663) <0.001
Multivariate analysis
 Age, year (> 55 versus ≤55) 0.749 (0.3359–1.564) 0.442
 Gender (male versus female) 0.838 (0.433–1.622) 0.600
 HBsAg (positive versus negative) 0.958 (0.495–1.854) 0.899
 Cirrhosis (yes versus no) 0.890 (0.498–1.590) 0.694
 Tumor Size (> 5 versus ≤5) 1.268 (0.692–2.326) 0.442
 TNM stage (III to IV versus I to II) 3.453 (1.814–6.573) <0.001
 Pin1 + RhoA/RhoC co-overexpression (yes versus no) 2.159 (1.078–4.325) <0.001